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Macrophages and monocytes are other immune cells in the mononuclear phagocyte system that have robust cell-autonomous rhythms (Scheiermann et al., 2013)

Because there is not enough high-quality human evidence to support routine clinical use and they are not currently approved for use in Humans by Health Canada or the FDA

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Microglia, neurons, astrocytes, and endothelial cells can release proinflammatory cytokines and chemokines, modulating adhesion molecules and transmigration of activated immune cells into the brain parenchyma (Jickling et al., 2018)